Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula c 6 h 4 (oh)(co 2 ch 3) it is the methyl ester of salicylic acid it is a colorless, viscous liquid with a sweet odor. Exp 4 - synthesis of salicylic acid from wintergreen oil study guide by chenderzahs includes 24 questions covering vocabulary, terms and more quizlet flashcards, activities and games help you improve your grades. Experiment 4: synthesis of salicylic acid from wintergreen oil abstract: the purpose of this experiment is to take methyl salicylate (wintergreen oil) and by heating it under reflux with naoh as a solvent, and then cooling the mixture with h2so4 as another solvent, synthesize salicylic acid. An additional step may be added to the synthesis of aspirin: conversion of oil of wintergreen (methyl salicylate) to salicylic acid (figure 2) this serves as figure 3: hydrolysis of oil of wintergreen 2 synthesis of salicylic acid from oil of wintergreen methyl salicylate salicylic acid molecular mass 15215 g mol-1 13812 g mol-1.
Methyl salicylate is an ester easily recognized by its odor and is known as oil of wintergreen because of its natural source this ester will be treated with aqueous base. Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens the compound was first extracted and isolated from plant species gaultheria procumbens in 1843. Synthesis description for preparation of methyl salicylate (wintergreen oil) a mixture of 304 g of salicylic acid (02 mole), 70 ml of methyl alcohol, and 7 ml of concentrated sulfuric acid.
To synthesize aspirin from salicylic acid, test for the purity of the product obtained, and determine the number of aspirin tablets that can be obtained from your preparation what commercial products contain oil of wintergreen [wintergreen life-savers, ben-gay, etc. The experiment is composed of two parts, the hydrolysis of methylsalicylate which is also known as oil of wintergreen is used to produce salicylic acid (part 1) and the made salicylic acid is then used to prepare acetylsalic acid which is the aspirin (part 2. Oil of wintergreen: synthesis and nmr analysis o introduction: when salicylic acid reacts with methanol in the presence of an acid catalyst, methyl salicylate, or oil of wintergreen, is produced according to the following equation: c oh oh + ch 3 oh h+ c och 3 o oh + h 2 o.
Methyl salicylate (oil of wintergreen) is a chemical that smells like wintergreen it is used in many over-the-counter products, including muscle ache creams it is related to aspirin methyl salicylate overdose occurs when someone swallows a dangerous amount of a product containing this substance this can be by accident or on purpose. This feature is not available right now please try again later. Synthesis of methyl salicylate from aspirin whose common name is oil of wintergreen you might expect that we’d synthesize this compound by reacting methyl alcohol (methanol) with salicylic.
Synthesis of aspirin: this lab is very time intensive and you must 'multitask' if you are going to finish the actual reaction to produce the aspirin only takes a minute or two, however, there is a lot of preparation before you are ready to run the reaction. The synthesis of aspirin (its chemical name being acetylsalicylic acid) and of oil of wintergreen (with its chemical name as methyl salicylate) both occur by addition of an ester to the molecules both syntheses have salicylic acid on the reactants side, however differ in the second reactant that ‘esterifies’ the salicylic acid. The synthesis of aspirin from wintergreen oil a “green” two step synthesis of aspirin aspirin -background • also known as acetylsalicylic acid (abbreviated asa), is a salicylate drug • aspirin was first isolated by felix hoffmann, a chemist with the german company bayer in. The synthesis of oil of wintergreen from salicylic acid: a fischer esterification emil fischer oct 9, 1852- july 15, 1919 german chemist attended university of bonn and university of strasbourg.
A single-pot procedure for the preparation of methyl salicylate (oil of wintergreen) from commercial aspirin tablets has been developed the synthesis proceeds via a tandem transesterification–fischer esterification using acidic methanol and can be carried out using either conventional or microwave heating. It is the two-step synthesis of aspirin starting from oil of wintergreen the mechanism for this synthesis provides examples of three major classes of chemical reactions: hydrolysis, condensation, and proton transfer.
On the other hand, oil of wintergreen or methylsalicylate is an external analgesic used to treat muscle aches, sprain, and strains having anti-inflammatory and pain-relieving effects as well (4) both the aspirin and methylsalicylate can be produced from salicylic acid, a natural occurring chemical in plants, consisting of two functional groups. Methyl salicylate, for example, is oil of wintergreen, isopentenyl acetate is oil of banana or pear, butyl butanoate smells like pineapple, propyl-2-methylpropanoate smells like rum and p- dimethylterephthalate and ethylene glycol (antifreeze) are used to make dacron. The purpose of the experiment was to make acetylsalicylic acid (aspirin) from methyl salicylate (oil of wintergreen) the amount of acetylsalicylic acid recovered was 17 grams the percent yield is 10494% of what the theoretical yield was.